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JoVE Journal
Neuroscience

This content is Open Access.

Neural Tube Closure in Mouse Whole Embryo Culture
 

Neural Tube Closure in Mouse Whole Embryo Culture

Article DOI: 10.3791/3132
October 21st, 2011

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Summary October 21st, 2011

A method allowing for direct pharmacological manipulation of mouse embryos during neurulation that bypasses maternal metabolism is described. The technique can be adapted to study different aspects of neurulation by varying the time point and pharmacological agent.

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