Sponge Injection
Sponge Injection - Related Videos
06:23
The Polyvinyl Alcohol Sponge Model Implantation
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Cited by 20 •
2012
A useful tool to analyze the effects of drugs, growth factors, and/or manipulated cells in an animal model of wound repair is described. This technique utilizes the properties of a polyvinyl alcohol (PVA) sponge to deliver and contain the desired treatment and also provide a platform to be excised and analyzed.
09:19
Intraperitoneal Injection into Adult Zebrafish
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Cited by 238 •
2010
We demonstrate intraperitoneal injection into adult zebrafish. We use a 10 μl NanoFil microsyringe controlled by a Micro4 controller and UltraMicroPump III. This demonstration includes the use of cold water as an anesthetic.
06:58
Zinc-Sponge Battery Electrodes that Suppress Dendrites
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Cited by 7 •
2020
The goal of the reported protocols is to create rechargeable zinc-sponge electrodes that suppress dendrites and shape change in zinc batteries, such as nickel–zinc or zinc–air.
02:56
Intrathoracic Injection: Compound Delivery to the Adult Zebrafish Heart
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2023
This video describes the technique of delivering compounds into the heart of adult zebrafish by using intrathoracic injection.
09:53
In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge
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Cited by 6 •
2018
Tissue-specific microRNA inhibition is a technology that is underdeveloped in the microRNA field. Herein, we describe a protocol to successfully inhibit the miR-181 microRNA family in myoblast cells from the heart. Nanovector technology is used to deliver a microRNA sponge that demonstrates significant in vivo cardio-specific miR-181 family inhibition.
FAQs
After placement, the gelatin sponge acts as a physical scaffold within the vessel and supports clot formation. This combination reduces flow through the selected vascular channel rather than relying on compression at the body surface. Because the material gradually resorbs, the occlusion is temporary, allowing circulation to potentially return to treated tissues as the sponge disappears.
Particle size is a key control variable in Sponge Injection because it affects where the material lodges within the vascular network. Appropriate sizing supports accurate targeting while reducing the chance that material will travel to unintended locations. This balance matters because the goal is to block the bleeding vessel without causing an unwanted embolization.
Image guidance and catheter delivery allow clinicians to direct particles or slurry toward a targeted site and observe the treatment process. This approach supports focused placement within the intended vessel while enabling monitoring for unintended embolization. It is particularly relevant when hemorrhage arises from a defined vascular source or when clinicians are treating a selected vascular lesion.
During image-guided embolization, clinicians prepare absorbable gelatin sponge as particles or a slurry and deliver it through a catheter. The selected form must support accurate placement at the target. Image guidance helps direct the injection into the intended vessel, while careful monitoring helps identify possible migration or unintended embolization during treatment.
Its main clinical roles are controlling hemorrhage, reducing blood loss during procedures, and treating selected vascular lesions. These applications place the technique within interventional radiology and surgery, where clinicians address a defined bleeding source or vascular abnormality. Appropriate use depends on accurate targeting and the expectation of temporary rather than permanent flow reduction.
After injection, clinicians monitor whether the targeted vessel has been adequately blocked and whether embolic material has reached an unintended location. As the gelatin resorbs, treated tissues may regain circulation, so the intervention provides temporary control rather than a lasting occlusion. This time-limited behavior can produce immediate bleeding control followed by possible restoration of blood flow.