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Journal / Medicine / The Polyvinyl Alcohol Sponge Model Implantation
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JoVE Journal Medicine
The Polyvinyl Alcohol Sponge Model Implantation
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The Polyvinyl Alcohol Sponge Model Implantation

Article DOI: 10.3791/3885-v • 06:23 min • April 18th, 2012
April 18th, 2012 •
1,2, 1,2, 1,2,3
1Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, 2The Department of Veterans Affairs Medical Center, 3Internal Medicine, Vanderbilt University School of Medicine

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Summary
Automatic Translation

A useful tool to analyze the effects of drugs, growth factors, and/or manipulated cells in an animal model of wound repair is described. This technique utilizes the properties of a polyvinyl alcohol (PVA) sponge to deliver and contain the desired treatment and also provide a platform to be excised and analyzed.

Tags

Polyvinyl Alcohol Sponge Implantation Wound Healing In Vivo Models Dead Space Models PVA Sponges Steel Wire Mesh Cylinders EPTFE Material Cellstick Limitations Granulation Tissue Formation Cellulose Sponge Silicon Tube Model Foreign Body Response
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