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The Polyvinyl Alcohol Sponge Model Implantation
JoVE Journal
Medicine
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JoVE Journal Medicine
The Polyvinyl Alcohol Sponge Model Implantation

The Polyvinyl Alcohol Sponge Model Implantation

DOI:
10.3791/3885-v

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06:23 min

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April 18, 2012

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, ,
1Department of Pathology, Microbiology and Immunology,Vanderbilt University School of Medicine, 2The Department of Veterans Affairs Medical Center, 3Internal Medicine,Vanderbilt University School of Medicine

Chapters

  • 00:05Title
  • 01:15Sponge Preparation
  • 02:12Surgical Procedure
  • 04:06Optional Injection and Sponge Removal
  • 04:57Results: Representative Sponge Sections
  • 06:00Conclusion

Summary

Automatic Translation

Automatic Translation

A useful tool to analyze the effects of drugs, growth factors, and/or manipulated cells in an animal model of wound repair is described. This technique utilizes the properties of a polyvinyl alcohol (PVA) sponge to deliver and contain the desired treatment and also provide a platform to be excised and analyzed.

Tags

Polyvinyl Alcohol SpongeImplantationWound HealingIn Vivo ModelsDead Space ModelsPVA SpongesSteel Wire Mesh CylindersEPTFE MaterialCellstickLimitationsCellulose SpongeSilicon Tube ModelForeign Body Response

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