Working Alliance

Working alliance is the collaborative relationship between a practitioner and a client, built through agreement on goals, shared tasks, and a trusting interpersonal bond. It works by aligning expectations and responsibilities: clear communication and consistent participation help the client engage with interventions, while feedback allows the partnership to adapt as treatment progresses. In neuroscience, studying the working alliance connects therapeutic interaction with processes such as social cognition, emotion regulation, motivation, and learning, using behavioral, physiological, or neuroimaging measures. Understanding these links may clarify why similar interventions produce different outcomes and support more responsive, effective care.

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JoVE Journal - Neuroscience

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JoVE Journal - Biology
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Cited by 9 •

2021

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JoVE Journal - Cancer Research

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Cited by 3 •

2022

The liquid biopsy has revolutionized our approach to oncology translational studies, with sample collection, quality, and storage being crucial steps for its successful clinical application. Here we describe a standardized and validated protocol for downstream circulating-free DNA applications that can be applied in most translational research laboratories.

Research

JoVE Journal - Engineering
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A System to Create Stable Nanoparticle Aerosols from Nanopowders

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Cited by 5 •

2016

We designed and developed an effective nanopowder aerosolization setup and operating protocol. The system generated nanoparticle aerosols with stable number concentrations and size distributions for long durations, requiring only small quantities of test material (min. 200 mg).

Mechanical Dissociation of Tissues for Single Cell Analysis Using a Motorized Device

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Cited by 3 •

2023

A general protocol for the combined enzymatic and semi-automated mechanical dissociation of tissues to generate single-cell suspensions for downstream analyses, such as flow cytometry, is provided. Instructions for the fabrication, assembly, and operation of the low-cost mechanical device developed for this protocol are included.

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