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Journal / Cancer Research / A Standardized Liquid Biopsy Preanalytical…
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Cancer Research

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JoVE Journal Cancer Research
A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications
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A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications

Article DOI: 10.3791/64123-v • 05:26 min • September 16th, 2022
September 16th, 2022 •
1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1
1The Liquid Biopsy and Biomarker Working Module, the Biomedical Research Network in Cancer (CIBERONC)

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Summary
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The liquid biopsy has revolutionized our approach to oncology translational studies, with sample collection, quality, and storage being crucial steps for its successful clinical application. Here we describe a standardized and validated protocol for downstream circulating-free DNA applications that can be applied in most translational research laboratories.

Tags

Liquid Biopsy Preanalytical Protocol Blood Samples Circulating-free DNA Standard Equipment Translational Laboratories Laboratory Staff Variability Precision Oncology Research Clinical Applications Non-cancer Diseases Plasma Or Serum Removal Centrifugation Technician
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