Brain Lateralization

Brain lateralization is the functional specialization of the brain’s two cerebral hemispheres, a principle that helps explain how neural organization shapes perception, cognition, emotion, and behavior. Although the hemispheres communicate through the corpus callosum, some functions show greater activity or efficiency in one hemisphere, such as language processing often associated with the left hemisphere and aspects of visuospatial processing often associated with the right. In psychology, studying brain lateralization uses behavioral experiments, neuropsychological assessments, and brain imaging to examine individual differences, development, and the effects of brain injury. This research clarifies how distributed neural systems support complex mental processes.

Brain Lateralization - Related Videos

Research

JoVE Journal - Neuroscience
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Lateral Fluid Percussion: Model of Traumatic Brain Injury in Mice

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Cited by 125 •

2011

Lateral fluid percussion (LFP), an established model of traumatic brain injury in mice, is demonstrated. LFP fulfills three major criteria for animal models: validity, reliability and clinical relevance. The procedure, consisting of surgical craniotomy, fixation of hub followed by induction of injury, resulting in focal and diffuse injuries, is described.

Research

JoVE Journal - Neuroscience

Live Imaging of the Ependymal Cilia in the Lateral Ventricles of the Mouse Brain

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Cited by 12 •

2015

Using high-resolution differential interference contrast (DIC) microscopy, an ex vivo observation of the beating of motile ependymal cilia located within the mouse brain ventricles is demonstrated by live-imaging. The technique allows a recording of the unique ciliary beating frequency and beating angle as well as their intracellular calcium oscillation pacing properties.

A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity

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Cited by 18 •

2017

This protocol presents a method for creating a large unilateral craniotomy over the temporal and parietal regions of the mouse cerebral cortex. This is especially useful for real time imaging over an expansive area of a cortical hemisphere.

Generating a Mouse Model of Traumatic Brain Injury Using a Lateral Fluid Percussion Device

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2025

The video demonstrates a method to generate a mouse model of traumatic brain injury (TBI) using a lateral fluid percussion device (LFPI). Upon anesthetizing the mouse, the brain is exposed by creating a window on the skull. A saline-filled cannula is attached to the window and is then connected to the LFPI. The pendulum of the device is released to create a pressure pulse that inflicts a traumatic brain injury.

Induction of Traumatic Brain Injury in a Rat Model Using a Lateral Fluid Percussion Device

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2025

This video demonstrates the induction of traumatic brain injury (TBI) in a rat using a lateral fluid percussion injury (FPI) device. The procedure involves creating a hole in the skull of an anesthetized rat to expose the dura mater, onto which a cannula is attached. The rat is then connected to the device, which generates a pressure wave that reaches the brain, mimicking TBI by causing neural cell death and vascular...

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