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JoVE Journal
Neuroscience

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Lateral Fluid Percussion
 

Lateral Fluid Percussion: Model of Traumatic Brain Injury in Mice

Article DOI: 10.3791/3063
August 22nd, 2011

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Summary August 22nd, 2011

Lateral fluid percussion (LFP), an established model of traumatic brain injury in mice, is demonstrated. LFP fulfills three major criteria for animal models: validity, reliability and clinical relevance. The procedure, consisting of surgical craniotomy, fixation of hub followed by induction of injury, resulting in focal and diffuse injuries, is described.

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