Catastrophic Stressors

Catastrophic stressors are extreme, potentially life-threatening events or conditions that overwhelm a person’s usual ability to cope and can have lasting psychological effects. They activate the stress response, including sympathetic nervous system arousal and hypothalamic-pituitary-adrenal axis signaling, which increase vigilance and release stress hormones such as cortisol. When intense or prolonged, these responses may disrupt emotional regulation, memory, sleep, and social functioning, contributing to acute stress reactions or post-traumatic stress disorder. In psychology, studying catastrophic stressors supports risk assessment, trauma-informed care, crisis intervention, and the development of strategies that strengthen resilience and recovery after disasters, violence, serious accidents, or other traumatic experiences.

Catastrophic Stressors - Related Videos

Education

JoVE Core - Introduction to Psychology

Types of Stressors

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2025

A stressor is any event, condition, or stimulus that triggers stress and causes a physical or psychological response in the body. Stressors can be categorized into three main types: catastrophes; significant life changes; and daily hassles, including social stress. Each can be detrimental to physical and mental well-being. Catastrophes Catastrophes refer to large-scale, unpredictable events that create overwhelming stress and a sense of threat. Examples include natural disasters like...

Research

JoVE Journal - Biochemistry

Extraction and Visualization of Protein Aggregates after Treatment of Escherichia coli with a Proteotoxic Stressor

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Cited by 6 •

2021

This protocol describes the extraction and visualization of aggregated and soluble proteins from Escherichia coli after treatment with a proteotoxic antimicrobial. Following this procedure allows a qualitative comparison of protein aggregate formation in vivo in different bacterial strains and/or between treatments.

Isolation of Stress-Adapted Bacteria through Single Colony Selection

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2025

Source: Jeong, H., et. al. Procedure for Adaptive Laboratory Evolution of Microorganisms Using a Chemostat. J. Vis. Exp. (2016).This video demonstrates the selective isolation and growth of stress-adapted bacteria from a culture exposed to prolonged stress conditions. The culture is plated on stressor-containing agar, and a single colony is selected to inoculate a liquid medium with the stressor. Absorbance is measured at regular intervals to monitor the growth and confirm the successful...

Research

JoVE Journal - Developmental Biology
Free Sample

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents

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Cited by 17 •

2017

Here, we present a protocol that provoked cortisol reactivity in a vulnerable adolescent Mexican American sample utilizing a modified version of the Trier Social Stress Test (TSST). Saliva samples were collected at baseline, 15, 30, and 45 min post-TSST onset. Future research could utilize this modified TSST with vulnerable youth.

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

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Cited by 88 •

2015

The unpredictable chronic mild stress (UCMS) protocol is a validated method for studying behavioral and physiological changes associated with chronic stress and depressive symptoms. Eight weeks of imposition of the UCMS protocol induces behavioral changes and poor health outcomes in rodents of either gender.

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