Tranquilizer Use

Tranquilizer use refers to the administration of medications that reduce central nervous system activity to relieve anxiety, agitation, or severe distress. Many tranquilizers, including benzodiazepines, enhance the action of gamma-aminobutyric acid at GABA-A receptors, slowing neuronal signaling and producing calming, sedative, and muscle-relaxing effects. In psychology and mental health care, these drugs may support short-term management of acute anxiety, panic, insomnia, or behavioral crises alongside psychological assessment and therapy. Their effects can include impaired attention, memory problems, tolerance, and physical dependence, making careful dosing, monitoring, and consideration of nonpharmacological approaches essential.

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JoVE Journal - Developmental Biology

Three-dimensional Angiogenesis Assay System using Co-culture Spheroids Formed by Endothelial Colony Forming Cells and Mesenchymal Stem Cells

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Cited by 14 •

2019

Three-dimensional co-culture spheroid angiogenesis assay system is designed to mimic the physiologic angiogenesis. Co-culture spheroids are formed by two human vascular cell precursors, ECFCs and MSCs, and embedded in collagen gel. The new system is effective for evaluating angiogenic modulators, and provides more relevant information to the in vivo study.

Separation and Identification of Conventional Microplastics from Farmland Soils

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Cited by 4 •

2025

Presented here is a method for extracting microplastics from soil and identifying their polymer types. The method has been optimized for execution, applicability, and cost-effectiveness. It lays a scientific foundation for standardizing the analytical method to identify microplastics in soils.

Research

JoVE Journal - Environment
Free Sample

JenaTron - An Experimental Approach to Study the Effects of Plant History and Soil History on Grassland Ecosystem Functioning

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Cited by 2 •

2025

Here we present a study established in the iDiv Ecotron, terrestrial mesocosm chambers with controlled environmental conditions above- and below-ground, to study the independent and interactive effects of plant history and soil history on ecosystem functioning of grassland communities along a plant diversity gradient.

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