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Developmental Biology
Morpholino Microinjection in Zebrafish
Description
Morpholino microinjection in zebrafish is a way to silence genes during development. Morpholinos are short oligonucleotides that bind to complementary mRNAs and block gene expression. Their unique chemistry makes them easy to produce and store, which can make them more cost effective than other gene silencing methods.
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Transcript
Técnicas de silenciamento genético são comumente usadas no campo da biologia do desenvolvimento. Abordagens de knockdown baseadas em morfolino permitem rotineiramente que os pesquisadores identifiquem e caracterizem genes envolvidos em processos celulares importantes. Os morfolinos antissenses são agora amplamente populares ...
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