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Developmental Biology
Morpholino Microinjection in Zebrafish
Description
Morpholino microinjection in zebrafish is a way to silence genes during development. Morpholinos are short oligonucleotides that bind to complementary mRNAs and block gene expression. Their unique chemistry makes them easy to produce and store, which can make them more cost effective than other gene silencing methods.
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Transcript
Gene silencing techniques are commonly used in the field of developmental biology. Morpholino-based knockdown approaches routinely allow researchers to both identify and characterize genes involved in important cellular processes. Antisense morpholinos are now widely popular in many model systems, including mice, chicks, and...
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