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Developmental Biology

How Transgenic Mice Reveal Gene Function

Description

Transgenesis is a genetic engineering method used in developmental biology to change gene expression. Scientists use it to study how genes affect development by altering gene function in model organisms.

One common strategy is to replace a gene with a nonfunctional copy. Another is to add a visua...

Transcript

Genetic engineering is a valuable tool used to modify genomes of model organisms in a process known as transgenesis. In developmental biology, this approach is often used to express modified genes that can be visualized in living tissues. Alternatively, genetic engineering can be used to prevent or disrupt protein expression...

Tags

TransgenesisKnockout MiceHomologous RecombinationEmbryonic Stem CellsFluorescent TaggingGenome EditingConditional KnockoutTissue Specific PromotersDevelopmental Biology

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