Olfactory Sensitivity Assessment
Olfactory Sensitivity Assessment - Related Videos
09:00
Olfactory Behavioral Testing in the Adult Mouse
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Cited by 68 •
2009
Fundamental, yet unique properties of the rodent olfactory system have led to its increasing study among biologists. A relatively simple assessment of its function is then also needed. Here we describe sensitive tests for the characterization of mouse olfactory sensitivity and preference.
06:40
Simple and Computer-assisted Olfactory Testing for Mice
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Cited by 9 •
2015
We present a simple and unbiased olfactory test in mice. With this protocol olfactory discrimination, preference, avoidance and sensitivity to a novel odor as compared to water can be assessed in single behavioral sessions. This method is indicated for a single experimenter and analysis is based on computer-assisted video processing.
04:28
Drosophila Y-maze Assay: A Method to Assess Olfactory Responses in Flies
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2023
This video describes a method to test olfactory exploratory behavior in the fruit fly, called the Y-maze. The featured protocol clip demonstrates how to set up and conduct the assay.
06:32
Quadruple Immunostaining of the Olfactory Bulb for Visualization of Olfactory Sensory Axon Molecular Identity Codes
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2017
Olfactory sensory neurons express a wide variety of axon-sorting molecules to establish proper neural circuitry. This protocol describes an immunohistochemical staining method to visualize combinatorial expressions of axon-sorting molecules at the axon termini of olfactory sensory neurons.
08:49
Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
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Cited by 23 •
2013
Loss of the righting reflex has long served as a standard behavioral surrogate for unconsciousness, also called hypnosis, in laboratory animals. Alterations in volatile anesthetic sensitivity caused by pharmacological interventions can be detected with a carefully controlled high-throughput assessment system, which may be adapted for delivery of any inhaled therapeutic.
FAQs
A detection threshold estimates the lowest odorant concentration at which an organism detects an odor under the assessment conditions. Because odorants are presented at controlled concentrations, researchers can relate a reported detection response to a defined exposure level. This provides a consistent basis for comparing olfactory sensitivity across individuals or experimental conditions.
Detection records whether an organism notices an odor, whereas discrimination evaluates whether it can distinguish among odors. Intensity ratings describe how strong the perceived odor seems. These measures capture different aspects of sensory response, so selecting among them helps researchers determine whether a study focuses on odor presence, odor differences, or perceived strength.
Comparing responses shows how odor perception varies among individuals or changes under different conditions. Such comparisons can identify differences in detection thresholds, discrimination, or perceived intensity without treating every response as equivalent. In environmental research, the results can also support investigations of changes in sensory function associated with measured odor exposure.
A basic workflow presents selected odorants at controlled concentrations and records the response measure relevant to the study. Researchers may document detection, discrimination, or an intensity rating, then use those observations to estimate detection thresholds or compare response patterns. Keeping concentration and response recording systematic makes results more useful for evaluating environmental conditions.
The assessment can support studies of odors associated with industrial activities, wastewater, agriculture, and other environmental sources. Researchers can use measured odor responses to characterize how these sources are perceived and to examine potential exposure-related differences. This makes the approach relevant when environmental quality includes odor conditions experienced by surrounding communities.
Results can help characterize odor impacts by linking controlled odorant responses with environmental exposure questions. They may contribute to monitoring strategies that evaluate environmental quality and potential effects on communities, while also providing a way to investigate changes in sensory function. The measurements therefore complement source-focused assessments with information about organismal odor response.