Cross-face Nerve Graft

Cross-face nerve grafting is a reconstructive microsurgical technique that restores movement to a paralyzed side of the face by linking it to functioning facial nerve fibers on the opposite side. Surgeons typically route a nerve graft, often harvested from the leg, beneath the skin across the face and connect one end to healthy facial nerve branches and the other to muscles or a free muscle transfer. Axons then regenerate through the graft, allowing electrical signals from the active side to activate the affected side. This approach can improve voluntary smiling and facial symmetry in patients with long-standing facial paralysis, supporting functional and psychosocial recovery.

Cross-face Nerve Graft - Related Videos

Research

JoVE Journal - Biology

Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord

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Cited by 21 •

2009

Traumatic injury to the spinal cord disrupts communication with the brain. To restore lost connectivity we utilize a peripheral nerve graft to provide a substratum for regenerating fibers in combination with neurotrophic factors and matrix-modulating enzymes to remove inhibitory molecules to promote long distance growth.

Construction of a Composite Regenerative Peripheral Nerve Interface in a Rat Model of Nerve Injury

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2025

Source: Svientek, S. R., et al. Fabrication of the Composite Regenerative Peripheral Nerve Interface (C-RPNI) in the Adult Rat. J. Vis. Exp. (2020).This video demonstrates the surgical construction of a composite regenerative peripheral nerve interface (C-RPNI) in a rat model of peripheral nerve injury. The procedure involves attaching a transected peroneal nerve to a muscle graft and overlaying it with a dermal skin graft to promote nerve regeneration. Over time, motor and sensory neurons...

Stromal Vascular Fraction-Enriched Fat Grafting for the Management of Symptomatic Neuromas

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2025

Source: Zimmermann, S., et.al. Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata. J. Vis. Exp. (2017)This video demonstrates the surgical procedure for neurolysis and stromal vascular fraction (SVF)-enriched fat grafting in the management of symptomatic neuroma. Neurolysis removes adhesion tissue to restore nerve gliding, while SVF-enriched fat grafting is applied around the nerve to create a protective barrier, support nerve healing, and enhance...

Mouse Models for Graft Arteriosclerosis

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Cited by 17 •

2013

We describe protocols for our mouse graft arteriosclerois (GA) models which involve interposition of a mouse vessel segment into a recipient of the same inbred strain. By backcrossing additional genetic changes into the vessel donor, the model can assess the effect of specific genes on GA.

Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata

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Cited by 8 •

2017

The purpose of the study is to illustrate the technical procedure of stromal vascular fraction (SVF)-enriched fat grafting as a novel treatment of symptomatic end-neuromata. This technique provides advantages of both the mechanical barrier and the biological action at the cellular level by the processed and concentrated SVF.

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