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Journal / Immunology and Infection / En enkel och effektiv strategi för att konstruera …
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
En enkel och effektiv strategi för att konstruera Mutant vacciniavirus vektorer
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En enkel och effektiv strategi för att konstruera Mutant vacciniavirus vektorer

Article DOI: 10.3791/54171-v • 09:16 min • October 30th, 2016
October 30th, 2016 •
*1, *2,3, 1, 1,2,3, 1,2,3
1Center for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, 2Sino-British Research Centre for Molecular Oncology, National Center for International Research in Cell and Gene Therapy, Zhengzhou University, 3School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University
* These authors contributed equally

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Vacciniavirus (VV) har använts i stor utsträckning inom biomedicinsk forskning och förbättring av människors hälsa. Den här artikeln beskriver en enkel, effektiv metod för att redigera VV-genomet med hjälp av en crispr-Cas9 systemet.

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Infektion vacciniavirus genomet redigering homolog rekombination crispr Cas9
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