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Induktion af Nefrotisk syndrom hos mus ved retrobulbær injektion af Doxorubicin og forebyggelse af volumen opbevaring af vedvarende frigivelse Aprotinin

Article DOI: 10.3791/57642-v • 07:38 min • May 6th, 2018
May 6th, 2018 •
1,2,3, 1,2,3
1Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Disease, Nephrology and Clinical Chemistry, University Hospital Tübingen, 2Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich, University Tübingen, 3German Center for Diabetes Research (DZD), University Tübingen

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Her beskriver vi induktion af eksperimentelle Nefrotisk syndrom i 129S1/SvImJ mus ved hurtig retrobulbær injektion af doxorubicin. Vi behandler også nefrotisk mus med vedvarende frigivelse piller indeholdende aprotinin for at hæmme urin Serin protease aktivitet og forhindre natrium fastholdelse.

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Medicin spørgsmål 135 eksperimentelle Nefrotisk syndrom doxorubicin mus retrobulbær aprotinin proteasuria
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