Interosseus Muscle

Interosseous muscles are small intrinsic muscles located between the metacarpal bones of the hand and metatarsal bones of the foot, where they support precise movement and stabilization of the digits. In the hand, dorsal interossei abduct the fingers, while palmar interossei adduct them toward the middle finger; together, they flex the metacarpophalangeal joints and help extend the interphalangeal joints through the extensor expansion. These muscles contribute to grip strength, fine motor coordination, and controlled finger positioning. Studying their anatomy and function helps explain hand biomechanics, assess peripheral nerve function, and understand impairment caused by injury or neurological disease.

Interosseus Muscle - Related Videos

Research

JoVE Journal - Medicine

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

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Cited by 12 •

2014

Dissociated atrophy of intrinsic hand muscles, termed the split hand, appears to be a specific feature of amyotrophic lateral sclerosis (ALS). Consequently, a novel neurodiagnostic test, termed the split hand index, was developed to quantify the clinical phenomenon of the split hand, which differentiated ALS from mimic disorders.

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

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Cited by 54 •

2012

We describe a method to directly measure muscle force, muscle power, contractile kinetics and fatigability of isolated skeletal muscles in an in vitro system using field stimulation. Valuable information on Ca2+ handling properties and contractile machinery of the muscle can be obtained using different stimulating protocols.

DNA Transfection of Mammalian Skeletal Muscles using In Vivo Electroporation

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Cited by 99 •

2009

We describe detailed procedures for the efficient transfection of plasmid DNA into the fibers of foot muscles of live mice using electroporation and the subsequent visualization of protein expression using fluorescence microscopy.

Research

JoVE Journal - Biology
Free Sample

Evaluation of Muscle Function of the Extensor Digitorum Longus Muscle Ex vivo and Tibialis Anterior Muscle In situ in Mice

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Cited by 73 •

2013

Changes in limb muscle contractile and passive mechanical properties are important biomarkers for muscle diseases. This manuscript describes physiological assays to measure these properties in the murine extensor digitorum longus and tibialis anterior muscles.

Measuring Compound Muscle Action Potentials in Mouse Forelimb Muscles In Vivo

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2025

This video demonstrates an in vivo technique for measuring compound muscle action potential (CMAP) in mice. It outlines the steps for setting up electrodes, stimulating forelimb neurons that innervate muscle fibers, and recording muscle responses. The technique assesses neuronal demyelination and functional neuron loss.

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