Bund Design

Bund design is the engineering planning of raised barriers and contained areas that prevent liquids from escaping into surrounding land, water, or infrastructure. It works by combining an appropriately sized enclosure with low-permeability materials, stable slopes, controlled drainage, and sufficient freeboard to retain anticipated spills, rainfall, or stored contents under defined conditions. In industrial and civil engineering, bunds protect people, equipment, and the environment around tanks, chemical stores, fuel facilities, and other liquid-handling sites. Sound design considers loading, seepage, settlement, access, inspection, and maintenance, helping facilities manage accidental releases, meet safety objectives, and support resilient site operation.

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Education

JoVE Core - Social Psychology

Group Design

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2020

The most basic experimental design involves two groups: the experimental group and the control group. The two groups are designed to be the same except for one difference— experimental manipulation. The experimental group gets the experimental manipulation—that is, the treatment or variable being tested—and the control group does not. Since experimental manipulation is the only difference between the experimental and control groups, we can be sure that any differences between the two are due to...

Research

JoVE Journal - Chemistry

Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles

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Cited by 4 •

2013

We describe a procedure for profiling salivary proteins using multiplexed microsphere-based antibody arrays. Monoclonal antibodies were covalently linked to fluorescent dye-encoded 4.5 μm polymer microspheres using carbodiimide chemistry. The modified microspheres were deposited in fiber-optic microwells to measure protein levels in saliva using fluorescence sandwich immunoassays.

From Theory to Design: The Role of Creativity in Designing Experiments

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2023

Source: Laboratories of Gary Lewandowski, Dave Strohmetz, and Natalie Ciarocco—Monmouth University Research studies come into being when a researcher speculates about human thought, emotions, or behavior, and has a theory that offers a potential explanation. Often the researcher’s theory is firmly situated in everyday common experiences that may not naturally lend themselves to direct empirical study. For example, researchers speculated that perception of a person on Facebook is influenced by...

Factorial Design

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2020

Factorial Analysis is an experimental design that applies Analysis of Variance (ANOVA) statistical procedures to examine a change in a dependent variable due to more than one independent variable, also known as factors. Changes in worker productivity can be reasoned, for example, to be influenced by salary and other conditions, such as skill level. One way to test this hypothesis is by categorizing salary into three levels (low, moderate, and high) and skills sets into two levels (entry level...

Directly Measuring Forces Within Reconstituted Active Microtubule Bundles

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Cited by 1 •

2022

Here, we present a protocol for reconstituting microtubule bundles in vitro and directly quantifying the forces exerted within them using simultaneous optical trapping and total internal reflection fluorescence microscopy. This assay allows for nanoscale-level measurement of the forces and displacements generated by protein ensembles within active microtubule networks.

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