Corneal Thickness
Corneal Thickness - Related Videos
08:37
Corneal Donor Tissue Preparation for Endothelial Keratoplasty
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Cited by 31 •
2012
Endothelial corneal transplantation is a surgical technique for treatment of posterior corneal diseases. Mechanical microkeratome dissection to prepare tissue results in thinner, more symmetric grafts with less endothelial cell loss and improved outcomes. Dissections can be performed at the eye bank prior to corneal transplantation surgery.
07:59
Murine Full-thickness Skin Transplantation
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Cited by 41 •
2017
Murine full-thickness skin transplantation is a well-established model to study rejection in an alloimmune setting. Here, we provide a tutorial of each step involved in performing a BALB/c-->C57BL/6 full-thickness skin transplant.
10:52
An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse
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Cited by 75 •
2014
Neovascularization (NV) of the cornea can complicate multiple visual pathologies. Utilizing a controlled, alkali-burn injury model, a quantifiable level of corneal NV can be produced for mechanistic study of corneal NV and evaluation of potential therapies for neovascular disorders.
08:17
Organotypic Culture of Full-thickness Adult Porcine Retina
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Cited by 19 •
2011
Here we describe a cost-effective technique for organotypic culture of adult porcine retina for seven days. Briefly, a sterile filter paper was used to lift the neural retina off from the RPE and place photoreceptor side up on an insert raised by a custom-made stand.
04:11
Laser-assisted Selective Ablation of Porcine Corneal Endothelial Cells: A Technique to Induce Focused Porcine Corneal Endothelial Injury for Ex Vivo Studies
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2025
This video demonstrates a non-invasive laser-assisted procedure to selectively damage the corneal endothelial cells in the porcine eye. The developed ex vivo model of endothelial cell damage can be used to study diseases of the corneal endothelium.
FAQs
Pachymetry quantifies corneal depth using either an optical approach or ultrasound-based measurement. These methods provide a numerical assessment rather than relying on visual inspection, helping clinicians evaluate ocular structure more consistently. Because thickness varies across the cornea and between individuals, the measurement must be interpreted in relation to the location assessed and the patient’s overall clinical context.
Corneal thickness can influence readings obtained with tonometry, the clinical measurement of intraocular pressure. Consequently, a pressure value may require contextual interpretation rather than being viewed in isolation. Incorporating pachymetry findings helps clinicians assess whether the pressure measurement accurately reflects the patient’s ocular situation, particularly when evaluating possible glaucoma risk.
Serial measurements can reveal changes in corneal thickness over time. An increase may contribute to the assessment of corneal swelling, while changing measurements during follow-up can help clinicians evaluate wound healing. The value lies in tracking a pattern rather than relying on one measurement, especially when the cornea has been affected by disease, injury, or a procedure.
Before refractive surgery, thickness measurements help clinicians consider whether altering corneal tissue is appropriate and safe. Pachymetry provides structural information that supports evaluation of the tissue available for a procedure. This assessment is relevant because refractive surgery changes the cornea, so documenting its thickness contributes to procedural planning and postoperative safety monitoring.
A clinician measures the cornea with pachymetry, using an optical or ultrasound-based instrument to quantify tissue depth. The resulting measurement is considered alongside the fact that thickness is not uniform across the cornea and differs among individuals. Depending on the clinical question, measurements may also be repeated over time to monitor structural change.
Clinicians use these measurements when evaluating glaucoma risk, corneal disorders, refractive-surgery eligibility, swelling, and wound healing. They also use the results to provide context for intraocular-pressure readings. Thus, pachymetry supports both diagnostic assessment and follow-up, particularly when corneal structure may affect interpretation of examination findings or change after treatment.