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Модель переходной трансгенерации IL-8 для<em> В Виво</em> Долгосрочный мониторинг воспалительных реакций
An IL-8 Transiently Transgenized Mouse Model for the <em>In Vivo</em> Long-term Monitoring of Inflammatory Responses
JoVE Journal
Иммунология и инфекции
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JoVE Journal Иммунология и инфекции
An IL-8 Transiently Transgenized Mouse Model for the In Vivo Long-term Monitoring of Inflammatory Responses

Модель переходной трансгенерации IL-8 для<em> В Виво</em> Долгосрочный мониторинг воспалительных реакций

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Сгенерировано автоматически
Please note that all translations are automatically generated. Click here for the English version.
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7,367 Views

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08:16 min

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July 07, 2017

DOI:

10.3791/55499-v

DOI:
10.3791/55499-v

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08:16 min
July 07, 2017

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7358 Views
, , , , , , , , , ,
1Department of Medicine, General Pathology Division, Cystic Fibrosis Translational Research Laboratory “D. Lissandrini”,University of Verona2Corporate Preclinical R&D,Chiesi Farmaceutici S.p.A.3Department of Diagnostic and Public Health, Microbiology Division,University of Verona4Dipartimento di Scienze Medico-Veterinarie,University of Parma5Department of Biomedical Biotechnological and Translational Sciences,University of Parma6Department of Computer Science,University of Verona7Department of Neurological, Biomedical and Movement Sciences,University of Verona8Cystic Fibrosis Regional Center (CFC),AOUI Verona

Резюме

Automatically generated

Описанный здесь способ позволяет визуализировать активацию IL-8-зависимого воспаления в легких мышей посредством неинвазивной биолюминесцентной визуализации (BLI). Одно и то же животное может быть подвергнуто BLI несколько раз в течение двух месяцев с момента доставки конструкции репортера люциферазы.

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Цитировать это СТАТЬЯ

Bergamini, G., Stellari, F., Sandri, A., M. Lleo, M., Donofrio, G., Ruscitti, F., Boschi, F., Sbarbati, A., Villetti, G., Melotti, P., Sorio, C. An IL-8 Transiently Transgenized Mouse Model for the In Vivo Long-term Monitoring of Inflammatory Responses. J. Vis. Exp. (125), e55499, doi:10.3791/55499 (2017).

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