Micro-CT Mapping of ACL Injury Damage in Rats

ACL injury in the knee can lead to post-traumatic osteoarthritis, or PTOA, which is joint damage that develops after an injury. About one-third of people show signs of PTOA on X-rays within the first decade after ACL injury. Although ACL reconstruction restores knee stability, it and current rehabilitation methods do not pre...

One of the most common knee injuries is the rupture or tear of the anterior cruciate ligament, also called the ACL, with almost one third of ACL injuries resulting in post-traumatic osteoarthritis, or PTOA, within a decade.

Rat models have been extensively used to study the effect of ACL injury on PTOA, as the rat knee joint is a close mod...