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Biology

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Molecular Biology

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Protein Function

How Ligands Attach to Proteins

Description

Ligands attach to proteins at specific binding sites on the protein surface. These sites let proteins interact with other molecules or ions and help them carry out important cell functions. Although many possible ligands may be nearby, only a matching ligand can bind to a given protein.

A ligand-...

Transcript

Activities of most proteins depend on their interactions with other molecules or ions,  known as ligands. Although ligands are able to bind to proteins, not every ligand binds to every protein. 

Instead, a ligand binds only to a specific region on a protein’s surface called the binding site. But how do ligand binding sites ensure selectiv...

Tags

Ligand Binding SiteProtein Ligand InteractionAmino Acid ArrangementNoncovalent InteractionsHydrogen BondingElectrostatic InteractionsVan Der Waals ForcesIn Silico ModelingIn Vitro AssaysBinding Site Selectivity

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