Transcription Regulators and Chromatin Access

Transcription regulators can help control gene expression by acting in different ways. Some proteins contact RNA polymerase directly. Others work through adaptors, mediators, histone-modifying proteins, and nucleosome remodelers.

Direct activation is seen in bacteria and in some eukaryotic genes....

In the eukaryotic cells, the initiation of transcription is a complex process that needs meticulous coordination between certain DNA elements and protein components. 

Besides RNA polymerase II and transcription factors, other regulatory factors are also involved in gene expression regulation during transcription initiation. 

Enhanc...