Nucleolus Structure and Ribosome Assembly

The nucleolus is the most prominent substructure inside the nucleus. It was once thought to be an isolated organelle that forms fibrils and granules. Later, in 1931, Heitz described its link with chromosomes and showed that its size and appearance change during the cell cycle.

Heitz also found co...

Within the nucleus are several organelles with specialized functions. Of these organelles, the nucleolus is one of the most prominent. 

A nucleolus is the site of ribosomal RNA, or rRNA, transcription and processing and ribosome assembly. Hence it is also referred to as a ‘ribosome producing factory.’

A membraneless organelle, the ...