Geminal Coupling in NMR Spectra

Geminal coupling in NMR spectra happens when two NMR-active nuclei are bonded to the same central atom. This is also called two-bond coupling. It is often seen between diastereotopic protons in chiral molecules and in unsymmetrical alkenes.

The central atom does not have to be NMR-active. Its ele...

Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling.

Examples include the coupling between diastereotopic protons in chiral molecules and unsymmetrical alkenes.

The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms....