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HIGH SCHOOL

Biology

Concept Videos

Cell Biology

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Cell Proliferation

Positive Regulators in Cell Growth

Description

Positive regulator molecules help cells move through the cell cycle. The cell cycle is the series of steps a cell uses to grow and divide. These molecules act as signals that support progress through each stage.

Two important examples are cyclins and cyclin-dependent kinases, or CDKs. Cyclins are...

Transcript

The positive regulator molecules promote the transition through various stages of the cell cycle via the interaction of two protein groups: cyclins and cyclin-dependent kinases or Cdks.

Mammalian cells contain around nine Cdks, with four of them, Cdk1, Cdk6, Cdk4, and Cdk2, involved in the cell cycle.

The activity and specificity o...

Tags

Cyclin Dependent KinasesCell Cycle CheckpointsCyclin Concentration FluctuationProto OncogenesGenetic MutationsMitotic Cell DivisionDNA Replication ErrorsCell Cycle ProgressionUncontrolled Cell Proliferation

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