Cell Size Homeostasis and Checkpoints

Cells coordinate growth and proliferation to keep cell size under control. Growth increases cell mass, while proliferation creates new cells. Together, these processes help cells maintain size homeostasis, which means keeping a stable size over time.

The cell cycle includes a checkpoint called th...

Cell size is a crucial factor in most fundamental processes, such as nutrient transport.

In an abnormally large cell, nutrients have to move longer distances to spread throughout the cell. As a result, nutrient diffusion becomes slow, causing the cell to die from nutrient starvation. 

Therefore, a healthy cell regulates its growth ...