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HIGH SCHOOL

Biology

Science Experiments

Basic Biology

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Biology I: yeast, <em>Drosophila</em> and <em>C. elegans</em>

RNAi in <em>C. elegans</em>

Description

RNA interference (RNAi) is a widely used technique in which double stranded RNA is exogenously introduced into an organism, causing knockdown of a target gene. In the nematode, C. elegans, RNAi is particularly easy and effective because it can be delivered simply by feeding the worms bacteria that express double stranded RNA (dsRNA) tha...

Transcript

RNA interference, or RNAi, is a widely used technique in which double stranded RNA is introduced to an organism, resulting in targeted gene silencing. The Nobel winning discovery of RNA interference allowed researchers to silence any C. elegans gene in order to determine its function. We can induce RNAi in C. e...

Tags

RNA InterferenceC ElegansGene KnockdownReverse Genetic ScreenBacterial FeedingAutomated ScreeningDevelopmental StudyPhenotypic AnalysisdsRNA PreparationWorm Synchronization

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