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HIGH SCHOOL

Biology

Science Experiments

Basic Biology

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Biology I: yeast, <em>Drosophila</em> and <em>C. elegans</em>

Feeding RNAi in C. elegans

Description

RNA interference, or RNAi, is a method for reducing the activity of a target gene. It works by introducing double-stranded RNA, or dsRNA, into an organism. The dsRNA matches a gene of interest and triggers targeted gene knockdown.

In the nematode C. elegans, RNAi is especially practical because t...

Transcript

RNA interference, or RNAi, is a widely used technique in which double stranded RNA is introduced to an organism, resulting in targeted gene silencing. The Nobel winning discovery of RNA interference allowed researchers to silence any C. elegans gene in order to determine its function. We can induce RNAi in C. e...

Tags

RNA InterferenceC ElegansGene KnockdownReverse Genetic ScreenBacterial FeedingAutomated ScreeningDevelopmental StudyPhenotypic AnalysisdsRNA PreparationWorm Synchronization

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