This is a free preview. For full access
Genetics
Chromatin Immunoprecipitation
Description
Histones are proteins that help organize DNA in eukaryotic nuclei by serving as “scaffolds” around which DNA can be wrapped, forming a complex called “chromatin”. These proteins can be modified through the addition of chemical groups, and these changes affect gene expression. Researchers use a technique called chromatin immu...
Show More
Transcript
Chromatin immunoprecipitation, or “ChIP,” is a technique used by researchers to assess protein-DNA interactions. Protein factors play important roles in the gene regulation; not only do they organize DNA in chromosomes, but they also bind to specific DNA sequences—called regulatory sites—to activate or repress expression. Duri...
Show More