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Biology

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Advanced Biology

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Genetics

Genome Editing

Description

A well-established technique for modifying specific sequences in the genome is gene targeting by homologous recombination, but this method can be laborious and only works in certain organisms. Recent advances have led to the development of “genome editing”, which works by inducing double-strand breaks in DNA using engineered...

Transcript

Genome editing comprises techniques with which researchers can “edit” or change a specific DNA sequence. These methods rely on the creation of small “cuts” in DNA, which cells attempt to repair, often incompletely. In this manner, scientists can induce mutations in targeted sequences with greater efficiency compared to classic...

Tags

Genome EditingCRISPR Cas9Zinc Finger NucleasesTALENsDNA RepairHomologous RecombinationNonhomologous End JoiningHomology Directed RepairDouble Strand BreaksGuide RNA Design

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