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Cell Biology
Cell Death Staining with Annexin V and PI
Description
Annexin V and propidium iodide (PI) staining helps identify how cells are dying. The method is used to tell apoptosis from necrosis. It does this by tracking two signals that change as a cell dies.
Annexin V is a protein that binds phosphatidylserine, a phospholipid that normally stays on the inn...
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Transcript
Annexin V and propidium iodide (PI) labeling of cells is a technique used to identify cell death, and distinguish between its different pathways: apoptosis, or programmed cell death, and necrosis. Cells undergo distinct morphological changes depending on the pathway. By identifying the specific conditions that lead a cell to u...
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