Lung Decellularization and Recellularization

Whole organs can be cultured ex vivo using specialized bioreactors to support repair or replacement of entire organs. In this approach, a donor organ is first stripped of all cells. What remains is the three-dimensional structure of the organ, which can then be repopulated with new cells.

The lun...

In vitro cultures of partial or whole organs are often used in order to accurately model tissue and organ function in various test conditions. Whole organ culture can involve the decellularization?of an excised organ or removal of cells?in order to utilize the native organ structure. This is followed by the recellularization with new cells. The ...