Abstract : Through this collection, I aim to unlock new biological insights using a biodiversity mining approach, uncovering potential breakthroughs in medicine and technology by pushing the boundaries of traditional research methods. Traditional model organisms are undoubtedly a foundational framework in biology and biomedical research. However, they have considerable limitations, as findings do not always translate to humans. This makes it imperative to study a broader range of species. A biodiversity mining approach will expand our understanding of biology, inspire new strategies to address today's unmet needs, and foster innovation.

A model organism is a non-human species studied to understand fundamental biological processes, offering insights that often translate to other species, particularly humans. Traditionally, organisms with key evolutionary positions have been chosen to serve as models for understanding these processes across species. However, the biology of these traditional models, limited to a handful of species, does not always generalize to humans. To fully grasp biological and evolutionary complexities, we must move beyond this limited selection and explore the vast diversity of life—nearly a million species on Earth—by broadening the range of organisms studied in the lab.

This Methods Collection seeks to bring together and document newly adapted, optimized, and widely applicable protocols, techniques, and toolkits for underutilized or emerging model organisms. The aim is to create practical, reproducible frameworks that enable researchers to seamlessly integrate new species into their work.

In line with my commitment to sustainability, inclusion, and diversity, this collection encourages contributions from scientists, particularly women of color, minorities, mothers in STEM, and those who are differently abled. Together, we can expand the horizons of biological research and pave the way for groundbreaking discoveries