Scott F. Leiser

University of Michigan

Research in Dr. Scott Leiser’s laboratory is focused on the molecular mechanisms of aging, with an emphasis on stress response and metabolism.  The Leiser lab works with multiple models, including Caenorhabditis elegans, in vitro tissue culture, and mice, to better understand the conserved mechanisms of aging. Recent research in his laboratory focuses on how organisms perceive and respond to environmental stress though cell non autonomous signaling mechanisms, and how these signals affect the health and longevity of the animal.  These studies have led to extensive work on the flavin containing monooxygenase family of enzymes, initially studied for xenobiotic metabolism but more recently found to have endogenous roles in metabolism and aging.  Dr. Leiser has been studying geroscience for nearly 20 years now, having completed his PhD at the University of Michigan with Dr. Richard Miller in 2009 and completing postdoctoral training with Dr. Matt Kaeberlein at the University of Washington in 2015. He is currently an Assistant Professor in the Molecular & Integrative Physiology Department within the Geriatrics Center at the University of Michigan.