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TOPICAL COLLECTIONS

Measuring Cardiovascular Rhythms: Innovations and Insights into Circadian Biology
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Abhilash Prabhat

Abhilash Prabhat

Department of Physiology, College of Medicine, University of Kentucky

Dr. Abhilash Prabhat is a postdoctoral researcher in the Department of Physiology at the College of Medicine, University of Kentucky, USA. He specializes in chronobiology using various vertebrate animal models, from avian species to preclinical mammalian systems. His expertise includes behavioral, physiological, and molecular biology techniques commonly used to assess biological rhythms. Currently, his research focuses on how environmental factors—such as light exposure, feeding schedules, and temperature—affect autonomic regulation of cardiovascular rhythms in mice. His work highlights the impact of misaligned light and food timing on heart rate and blood pressure, with an emphasis on sex-specific responses. He is also leading a project investigating time-restricted feeding as a strategy to mitigate arrhythmias in diabetic mice.

Collection Overview

Circadian rhythms are a fundamental feature of biological systems. In cardiovascular research, growing evidence supports a robust circadian regulation of cardiac electrophysiology (e.g., RR and QT intervals), heart rate, and blood pressure. However, modern lifestyle factors—such as increased exposure to artificial light at night, disrupted sleep, and irregular feeding patterns—have altered these rhythms, potentially contributing to the rise in cardiometabolic disorders.

This collection seeks to advance our understanding of cardiovascular circadian rhythms through methodological innovation and original research. We invite submissions presenting new experimental techniques, refinements of existing methods, and studies demonstrating the application of these tools in both physiological and in health and disease. The collection will include original research articles as well as methods papers, spanning a range of model systems including Drosophila, rodents (mice and rats), and humans.

By bringing together methodological advances and empirical studies, this collection aims to provide a comprehensive resource for researchers studying circadian biology in the cardiovascular system.

Articles

<em>In Vivo</em> Telemetry to Record Long-Term Cardiovascular Parameters, Temperature, and Activity in Spinal Cord Injury Rat Models
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In Vivo Telemetry to Record Long-Term Cardiovascular Parameters, Temperature, and Activity in Spinal Cord Injury Rat Models

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2026

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