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TOPICAL COLLECTIONS

Research Methods for the Evaluation of Phytochemicals

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Libo Tan

Libo Tan

University of Alabama

Dr. Libo Tan is an Assistant Professor in the Department of Human Nutrition at the University of Alabama. Dr. Tan's research focuses on the bioavailability, pharmacokinetics, and biological activities of micronutrients and phytochemicals, particularly those associated with neonatal development, adipose tissue metabolism, or glucose homeostasis. Using in vivo and in vitro models, Dr. Tan’s research group investigates how various physiological or diseased states affect the pharmacokinetics and/or bioeffects of those bioactive compounds. They are also interested in exploring techniques, such as nano-encapsulation, that may improve the bioavailability and optimize the bioactivities of phytochemicals. Dr. Tan earned her PhD in Nutritional Sciences at the Pennsylvania State University in 2013, and Bachelor's degree in Biological Sciences at Shandong University, China in 2007.

Collection Overview

Phytochemicals are nonnutritive compounds in plants that have health-protective benefits. A diet rich in plant foods, including certain fruits, vegetables, whole grains, nuts, and legumes, will provide various phytochemicals, including phenolic compounds, terpenoids, carotenoids, and other antioxidants. The intake of phytochemicals has been associated with protection from and/or treatment of cardiovascular disease, certain cancers, diabetes, and hypertension, among many other diseases and conditions. As such, research efforts on the profiling of phytochemicals and on the understand of their mechanisms of action and health benefits are highly important.

This Methods Collection will focus on the methods used to study phytochemicals, including but not limited to the screening, extraction, isolation, quantification, and characterization of phytochemicals from various sources, as well as the investigation on the bioavailability, metabolism, pharmacokinetics, molecular mechanism, and functionality of phytochemicals utilizing in vitro or in vivo models.

Articles

A Generalized Method for Determining Free Soluble Phenolic Acid Composition and Antioxidant Capacity of Cereals and Legumes
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A Generalized Method for Determining Free Soluble Phenolic Acid Composition and Antioxidant Capacity of Cereals and Legumes

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Cited by 7

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2022

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Abstracts

In vivo assessment of cytotoxic effects of Syzygium cumini leaves extract on normal human oral keratinocytes

Marcelo Boriollo*1

1Universidade Estadual de Campinas

In vitro assessment of cytotoxic effects of Pleurotus sajor-caju-extract mediated synthesis of nanoparticles

Raghvendra Bohara *1

1D.Y.Patil Education Society, Kolhapur, India