Human Grasping

Human grasping is the coordinated use of the hand and fingers to secure, hold, and manipulate objects, making it a central behavior for interacting with the physical world. It depends on visual and tactile information that guide motor planning, hand shaping, and the graded forces needed to oppose an object’s weight, size, and surface friction. As the hand closes, sensory feedback continuously updates grip force and finger position to maintain stability without unnecessary effort. Studying human grasping helps explain motor control, perception-action coupling, and adaptive behavior, while informing rehabilitation strategies, prosthetic hand design, and robotic manipulation.

Human Grasping - Related Videos

Research

JoVE Journal - Behavior
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Estimation of Contact Regions Between Hands and Objects During Human Multi-Digit Grasping

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Cited by 9 •

2023

When we grasp an object, multiple regions of the fingers and hand typically make contact with the object's surface. Reconstructing such contact regions is challenging. Here, we present a method for approximately estimating the contact regions by combining marker-based motion capture with existing deep learning-based hand mesh reconstruction.

Research

JoVE Journal - Behavior

Frame-by-Frame Video Analysis of Idiosyncratic Reach-to-Grasp Movements in Humans

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Cited by 7 •

2018

This protocol describes how to use frame-by-frame video analysis to quantify idiosyncratic reach-to-grasp movements in humans. A comparative analysis of reaching in sighted versus unsighted healthy adults is used to demonstrate the technique, but the method can also be applied to the study of developmental and clinical populations.

Dissection of Human Retina and RPE-Choroid for Proteomic Analysis

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Cited by 7 •

2017

The human retina is composed of functionally and molecularly distinct regions, including the fovea, macula, and peripheral retina. Here, we describe a method using punch biopsies and manual removal of tissue layers from a human eye to dissect and collect these distinct retinal regions for downstream proteomic analysis.

Research

JoVE Journal - Neuroscience
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Behavioral Assessment of Manual Dexterity in Non-Human Primates

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Cited by 45 •

2011

As manual dexterity is a prerogative mainly of primates, behavioral tasks have been developed in macaque monkeys. Four reach and grasp prehension tasks, measuring hand manipulation ability and force, allow to establish functional recovery after a lesion of the central nervous system and to test the effect of a treatment.

Research

JoVE Journal - Biology
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In Vivo Modeling of the Morbid Human Genome using Danio rerio

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Cited by 66 •

2013

Here, we present a systematic approach for developing physiologically relevant, sensitive and specific in vivo assays for interpreting variation in human pathology. Transient genetic manipulation via microinjection of WT and mutant human mRNA and morpholino (MO) antisense oligonucleotides harness the tractability of the developing zebrafish embryo to rapidly assay pathogenic mutations, especially, but not exclusively, in the context of human developmental disorders.

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