Perinatal Mood Disorders

Perinatal mood disorders are mental health conditions occurring during pregnancy or after childbirth, including depression and anxiety that can alter emotional regulation, behavior, relationships, and daily functioning. They emerge through interacting biological and psychosocial factors: rapid reproductive hormone changes, stress physiology, sleep disruption, and social demands can affect neural systems involved in mood regulation. In behavior-focused research and clinical care, symptom assessment, screening, and interventions such as psychotherapy, social support, and medication help identify risk, reduce distress, strengthen parent-infant relationships, and improve outcomes for parents and children.

Perinatal Mood Disorders - Related Videos

Education

JoVE Science Education - Psychology

An Introduction to Modeling Behavioral Disorders and Stress

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2023

Recently, it has been discovered that behavioral conditions such as, depression, anxiety and stress-response have a neurological basis. Understanding the biological underpinnings of these conditions may help scientists in developing more effective therapies to treat these disorders. Typically, rodent models are used in this field and behavioral scientists create these models using interventions like drug administration or surgery. It is important to understand how to create and evaluate rodent...

Research

JoVE Journal - Biology

The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia

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Cited by 48 •

2008

The postnatal rat model for hypoxic-ischemic brain injury is a well-established model of human neonatal hypoxic ischemic encephalopathy (HIE). In this article, we describe the model of HIE in post-natal rat pups.

Traits, Mood, and Subjective Wellbeing

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2025

Subjective well-being (SWB) refers to an individual's self-evaluation of their overall life satisfaction, happiness, and fulfillment. This multifaceted construct is typically assessed by analyzing the balance of positive and negative emotions alongside perceptions of life satisfaction. Personality traits such as neuroticism and extraversion are strongly associated with variations in SWB, offering critical insights into the underlying mechanisms of emotional well-being. Neuroticism and Emotional...

Using In Vivo and Tissue and Cell Explant Approaches to Study the Morphogenesis and Pathogenesis of the Embryonic and Perinatal Aorta

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2017

Protocols for studying the embryonic and perinatal murine aorta using in vivo clonal analysis and fate mapping, aortic explants, and isolated smooth muscle cells are detailed here. These diverse approaches facilitate the investigation of the morphogenesis of the embryonic and perinatal aorta in normal development and the pathogenesis in disease.

Noninvasive Electrocardiography in the Perinatal Mouse

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Cited by 3 •

2020

Here, we present a noninvasive electrocardiography (ECG) protocol, optimized for early postnatal mice, that does not require the use of anesthetics.

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