Coc Foil

COC foil, made from cyclic olefin copolymer, is a transparent thermoplastic film used to construct lightweight, chemically stable components for biochemical and microfluidic research. Its low water absorption, optical clarity, and resistance to many solvents help preserve fluid handling performance while allowing researchers to monitor reactions through the film. These properties support lab-on-a-chip devices, microfluidic cartridges, biosensors, and optical assays that require precise liquid control and reliable signal detection. COC foil can therefore improve device integration, sample analysis, and reproducibility in applications ranging from diagnostic testing to biochemical experimentation.

Coc Foil - Related Videos

Research

JoVE EoE - Large Animal Models

3D Culture of Porcine COCs: A Procedure to Encapsulate Cumulus Oocyte Complexes in Fibrin-alginate Polymer Hydrogel Beads

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2025

This video describes the protocols for encapsulating porcine cumulus-oocyte complexes (COCs) in fibrin-alginate beads to establish a 3D culture. This in-vitro maturation system maintains normal cell-to-cell communication, ensuring oocyte maturation and retaining viability.

Porcine Cumulus Oocyte Complex Isolation: A Technique to Isolate Cumulus Oocyte Complex from Porcine Ovarian Follicle for In Vitro Fertilization

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2025

This video describes the technique to isolate the cumulus-oocyte complex or COC from porcine ovaries. The isolated intact COC can be used to carry out the in vitro fertilization - the assisted reproductive technique for developing fertility treatments.

Liquid Marble Microbioreactor System: A 3D Culture Protocol for Encapsulation of Porcine Oocytes

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2025

In this video, we describe a protocol for the encapsulation of porcine oocytes in hydrophobic microbioreactors.

Analysis of Chromosome Segregation, Histone Acetylation, and Spindle Morphology in Horse Oocytes

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Cited by 21 •

2017

This manuscript describes an experimental approach to morphologically and biochemically characterize horse oocytes. Specifically, the present work illustrates how to collect immature and mature horse oocytes by ultrasound-guided ovum pick-up (OPU) and how to investigate chromosome segregation, spindle morphology, global histone acetylation, and mRNA expression.

Research

JoVE Journal - Bioengineering
Free Sample

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape

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Cited by 12 •

2014

Two adjacent fluids passing through a grooved microfluidic channel can be directed to form a sheath around a prepolymer core; thereby determining both shape and cross-section. Photoinitiated polymerization, such as thiol click chemistry, is well suited for rapidly solidifying the core fluid into a microfiber with predetermined size and shape.

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