Biopolymer Electrospinning
Biopolymer Electrospinning - Related Videos
07:58
Electrospinning of Silk Biomaterials
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2023
Silk fibers have been processed and used to create fabrics and threads for centuries. However, the solubilizing of silk fibers, thereby turning it into a versatile pre-polymer solution is a much newer technology. Solubilized silk can be processed in many different ways to create a biocompatible material with controllable mechanical properties. This video introduces the processing of silk from silk worm cocoons, and shows how the silk solution can be used to create a fiber mat via...
08:13
Preparation of Biopolymer Aerogels Using Green Solvents
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Cited by 44 •
2016
A new way for the production of biopolymer-based aerogels by carbon dioxide (CO2) induced gelation is shown. The technique utilizes pressurized carbon dioxide (5 MPa) for the production of biopolymer hydrogels and supercritical CO2 (12 MPa) to convert gels into aerogels. The only solvents needed besides CO2 are water and ethanol.
07:06
Methods for the Self-integration of Megamolecular Biopolymers on the Drying Air-LC Interface
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Cited by 4 •
2017
A method for the drying-induced self-integration of megamolecular biopolymers on the air-liquid crystalline interface is provided here. This methodology will be useful not only for understanding the macroscopic potentials of biopolymers, but also as an evaluation method for soft materials in biomedical and environmental fields.
06:55
Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
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Cited by 10 •
2016
In the protocol, we present a method to manufacture a small caliber stent-graft by sandwiching a balloon expandable stent between two electrospun nanofibrous polyurethane layers.
01:18
Thermally Responsive Biopolymer-Based Inhibition of Tumor Progression in a Rat Model
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2025
Begin with an anesthetized rat bearing a brain tumor composed of proliferating tumor cells.Expose the rat’s skull and create a hole to reveal the brain region with the tumor.Take a thermally responsive biopolymer fused with a cell-penetrating peptide and an inhibitor of c-myc, an oncogenic protein.Inject the biopolymer into the femoral vein of the hind limb for delivery to the brain.Apply infrared light through the skull hole to heat the tumor site, which induces biopolymer aggregation along...
FAQs
The electric field draws the polymer liquid into a stretched jet that travels from the needle toward the grounded collector. During this movement, solvent evaporates before deposition, converting the traveling material into solid fibers. The extent of stretching and evaporation helps determine the resulting fiber diameter and contributes to formation of the porous, nonwoven scaffold architecture.
These structural features determine how closely a scaffold can reproduce selected aspects of the extracellular matrix. Biopolymer electrospinning allows researchers to adjust fiber diameter, alignment, and porosity rather than producing a single fixed architecture. Such control is relevant when designing materials intended to support tissue engineering or wound-healing applications with different structural requirements.
Collagen, gelatin, chitosan, and silk fibroin provide different biopolymer options for constructing electrospun materials. The selected polymer contributes to the scaffold’s material composition, while processing can be used to tune properties such as degradation. This combination lets bioengineers connect the choice of biological material with the intended function of a tissue scaffold, delivery platform, or sensing material.
A researcher prepares a biopolymer solution or melt and places it in a setup containing a needle, a high-voltage source, and a grounded collector. Applying voltage creates a charged liquid jet, which stretches as it moves across the gap. Solvent evaporation then enables the material to deposit as a porous fiber mat on the collector.
Researchers can adjust fiber diameter, alignment, porosity, and degradation to match the goals of a bioengineering design. These variables describe both the physical organization of the deposited mat and how the material changes over time. Controlling them helps tailor scaffolds for biological settings where architecture and material persistence influence the usefulness of the fabricated construct.
The technique is useful when a project requires a fibrous, porous material that can be adapted for biological function. Its applications include tissue-engineering scaffolds, wound-healing materials, drug-delivery systems, and biosensors. In each case, the method links controllable fiber-mat fabrication with a targeted biomedical purpose, allowing material structure and degradation to be considered alongside application needs.