Chitosan Film Fabrication

Chitosan film fabrication is a method for producing thin, biodegradable polymer films from chitosan, a deacetylated derivative of chitin, for use in bioengineering and related fields. The process typically dissolves chitosan in a dilute acidic solution, spreads the polymer mixture onto a surface, and removes the solvent by controlled drying to form a continuous film; additives or crosslinking treatments can adjust its strength, flexibility, and permeability. These films provide versatile platforms for wound dressings, drug delivery systems, tissue-engineering scaffolds, and protective coatings. Their biocompatibility, biodegradability, and tunable material properties make fabrication conditions important for designing application-specific biomedical devices.

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Research

JoVE Journal - Bioengineering

Fabrication and Application of Rose Bengal-chitosan Films in Laser Tissue Repair

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Cited by 23 •

2012

Sutures are usually needed to repair tissue during surgical procedures. However, their application can be problematic as they are invasive and may damage tissue. The fabrication and application methods of a novel tissue adhesive are here reported. This adhesive film is laser-activated and does not require the use of sutures.

Capillary Electrophoresis to Monitor Peptide Grafting onto Chitosan Films in Real Time

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Cited by 1 •

2016

Free solution capillary electrophoresis is a fast, cheap and robust analytical method that enables the quantitative monitoring of chemical reactions in real time. Its utility for rapid, convenient and precise analysis is demonstrated here through analysis of covalent peptide grafting onto chitosan films for improved cell adhesion.

A Chitosan Based, Laser Activated Thin Film Surgical Adhesive, 'SurgiLux': Preparation and Demonstration

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Cited by 32 •

2012

The fabrication of a novel, flexible thin film surgical adhesive from FDA approved ingredients, chitosan and indocyanine green is described. Bonding of this adhesive to collagenous tissue through a simple activation process with a low-powered infra-red laser is demonstrated.

Fabrication and Optimization of Type II Silicon Clathrate Films

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2025

The two-thermal annealing method enables the fabrication of thin films of type II semiconductor silicon clathrate. Post-synthesis treatments, including thermal pressing and reactive ion etching, were performed to improve the material properties. This approach provides an accessible pathway for fabricating tunable clathrate films suitable for next-generation electronic and photonic devices.

Fabrication of Large-area Free-standing Ultrathin Polymer Films

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Cited by 10 •

2015

We describe a method for the fabrication of large-area (up to 13 cm diameter) and ultrathin (as thin as 8 nm) polymer films. Instead of using a sacrificial interlayer to delaminate the film from its substrate, we use a self-limiting surface treatment suitable for arbitrarily large areas.

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