Dynamic Mechanical Analyzer

A Dynamic Mechanical Analyzer is an instrument that characterizes how materials deform and dissipate energy under controlled mechanical loading, making it valuable for evaluating biomaterials and tissue-like materials. It applies a small oscillating force or displacement while measuring the resulting strain, allowing calculation of storage modulus, loss modulus, and damping across selected temperatures or frequencies. In bioengineering, dynamic mechanical analysis helps assess the viscoelastic behavior of hydrogels, polymers, tissue scaffolds, and other engineered materials under conditions that mimic physiological loading. These measurements support material selection, formulation optimization, and the design of structures with mechanical properties suited to specific biological environments.

Dynamic Mechanical Analyzer - Related Videos

Research

JoVE Journal - Bioengineering

Microfabricated Platforms for Mechanically Dynamic Cell Culture

0 Views •

Cited by 3 •

2010

In this protocol, we demonstrate the fabrication of a microactuator array of vertically displaced posts on which the technology is based, and how this base technology can be modified to conduct high-throughput mechanically dynamic cell culture in both two-dimensional and three-dimensional culture paradigms.

Use of Immunolabeling to Analyze Stable, Dynamic, and Nascent Microtubules in the Zebrafish Embryo

0 Views •

Cited by 1 •

2017

Immunolabeling methods to analyze distinct populations of microtubules in the developing zebrafish brain are described here, which are broadly applicable to other tissues. The first protocol outlines an optimized method for immunolabeling stable and dynamic microtubules. The second protocol provides a method to image and quantify nascent microtubules specifically.

Research

JoVE Journal - Chemistry
Free Sample

Analyzing Melts and Fluids from Ab Initio Molecular Dynamics Simulations with the UMD Package

0 Views •

Cited by 2 •

2021

Melts and fluids are ubiquitous vectors of mass transport in natural systems. We have developed an open-source package to analyze ab initio molecular-dynamics simulations of such systems. We compute structural (bonding, clusterization, chemical speciation), transport (diffusion, viscosity) and thermodynamic properties (vibrational spectrum).

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry

0 Views •

Cited by 15 •

2013

Protein conformation and dynamics are key to understanding the relationship between protein structure and function. Hydrogen exchange coupled with high-resolution mass spectrometry is a versatile method to study the conformational dynamics of proteins as well as characterizing protein-ligand and protein-protein interactions, including contact interfaces and allosteric effects.

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads

0 Views •

Cited by 3 •

2017

Cell surface adhesions are central in mechanotransduction, as they transmit mechanical tension and initiate the signaling pathways involved in tissue homeostasis and development. Here, we present a protocol for dissecting the biochemical pathways that are activated in response to tension, using ligand-coated magnetic microbeads and force application to adhesion receptors.

View All Results

FAQs

Related Topics