Low-cost Fabrication

Low-cost fabrication is the design and production of devices, structures, or experimental systems using inexpensive materials, accessible tools, and simplified manufacturing methods. In bioengineering, it can combine techniques such as 3D printing, laser cutting, paper-based assembly, and mold-based casting to create functional components with controlled geometry and reproducible workflows. These approaches reduce equipment and material costs while supporting rapid prototyping of microfluidic devices, tissue-engineering scaffolds, biosensors, and educational models. By making fabrication more accessible, low-cost methods can expand research capacity, enable point-of-care technologies, and accelerate testing in settings with limited laboratory infrastructure.

Low-cost Fabrication - Related Videos

Research

JoVE Journal - Bioengineering

Rod-based Fabrication of Customizable Soft Robotic Pneumatic Gripper Devices for Delicate Tissue Manipulation

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Cited by 10 •

2016

This protocol describes a rod-based approach, combining 3D-printing and soft lithography techniques for fabricating the soft gripper devices. This approach eliminates the need for an external air source by incorporating a chamber component and reduces the chance of occlusion during the sealing process, particularly for miniaturized pneumatic channels.

Research

JoVE Journal - Bioengineering
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Low-Cost Cryo-Light Microscopy Stage Fabrication for Correlated Light/Electron Microscopy

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Cited by 11 •

2011

We demonstrate the fabrication of a low-cost cryogenic stage designed to fit most reflected light microscopes. This lab-built cryogenic stage enables efficient and reliable correlative imaging between cryo-light and cryo-electron microscopy.

Development of a Low-cost Epimysial Electromyography Electrode: A Simplified Workflow for Fabrication and Testing

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2024

Our purpose was to provide an updated, easy-to-follow guide on the fabrication and testing of epimysial electromyography electrodes. To that end, we provide instructions for material sourcing and a detailed walkthrough of the fabrication and testing process.

Research

JoVE Journal - Engineering
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Fabrication of a Low-Cost, Fiber-Coupled, and Air-Spaced Fabry-Pérot Etalon

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Cited by 2 •

2023

This protocol describes the construction of a low-cost, discrete, fiber-coupled, and air-spaced Fabry-Perot etalon with various applications, such as in trace-gas spectroscopy. The fabrication is possible in any facility with standard optical laboratory equipment available.

Fabricating Cotton Analytical Devices

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2016

To investigate simple fabrication approaches for multiple assay needs, we created a fluid-absorbing channel system made of cotton material. This device was used to establish a multiple detection platform, and solve contamination issues that commonly affect lateral flow-based biomedical devices, for clinical urinalysis of nitrite, total protein, and urobilinogen.

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