Photothermal Convection Suppression

Photothermal convection suppression is the control of fluid motion caused by localized heating when materials absorb light and convert it into thermal energy. The resulting temperature gradients can produce buoyancy-driven convection, which is reduced by regulating illumination, limiting the heated region, increasing fluid confinement or viscosity, and managing heat dissipation. In bioengineering, suppressing these flows improves the spatial and thermal precision of photothermal processes in microfluidic systems, biomaterials, and cell-based experiments. Better control can minimize unintended transport, protect nearby biological structures, and support reproducible thermal manipulation, imaging, and therapeutic strategies.

Photothermal Convection Suppression - Related Videos

Research

JoVE Journal - Engineering

Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties

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Cited by 5 •

2016

A protocol is presented for the synthesis and preparation of nanoparticles consisting of electroactive polymers.

Submillisecond Conformational Changes in Proteins Resolved by Photothermal Beam Deflection

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Cited by 1 •

2014

Here we report an application of the photothermal beam deflection technique in combination with a caged calcium compound, DM-nitrophen, to monitor microsecond and millisecond dynamics and energetics of structural changes associated with the calcium association to a neuronal calcium sensor, Downstream Regulatory Element Antagonist Modulator.

Convection-Enhanced Delivery of Antibodies into a Mouse Brain

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2025

This video demonstrates a convection-enhanced delivery (CED) technique for antibody delivery into the mouse brain. The skull of an anesthetized mouse is exposed, and a burr hole is created at the target area for antibody delivery. A step catheter containing antibodies is inserted at the target site, and via an infusion pump, a pressure gradient is created to deliver antibodies at a controlled rate.

Research

JoVE Journal - Biology
Free Sample

Rapid PCR Thermocycling using Microscale Thermal Convection

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Cited by 21 •

2011

We describe a novel method to perform DNA replication via the polymerase chain reaction (PCR). Thermal convection is harnessed to continuously shuttle reagents between denaturing, annealing, and extension conditions by maintaining opposing surfaces of the reactor at constant temperature. This inherently simple design promises to make rapid PCR more accessible.

Education

JoVE Science Education - Engineering

Using a Tray Dryer to Investigate Convective and Conductive Heat Transfer

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2023

Source: Michael G. Benton and Kerry M. Dooley, Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA Dryers are utilized in numerous industrial processes. The function of a dryer is to use heat transfer processes to dry solids. A variety of dryer types exist. Adiabatic dryers use convection and direct contact with gases to dry solids, whereas non-adiabatic dryers use methods other than heated gas contact to dry1, including conduction, radiation, and radio frequency...

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