Shear Wave Imaging
Shear Wave Imaging - Related Videos
07:13
Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH
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Cited by 14 •
2021
This protocol describes the use of an enhanced ultrasound technique to non-invasively observe and quantify liver tissue changes in rodent models of nonalcoholic fatty liver disease.
09:32
Standing Waves
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2023
Source: Arianna Brown, Asantha Cooray, PhD, Department of Physics & Astronomy, School of Physical Sciences, University of California, Irvine, CA Standing waves, or stationary waves, are waves that appear not to propagate and are produced by the interference of two waves traveling in opposite directions with the same frequency and amplitude. These waves appear to vibrate up and down with no linear movement and are most easily identified in vibrating finite media like a plucked guitar string,...
04:53
A Novel Capsulorhexis Technique Using Shearing Forces with Cystotome
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Cited by 5 •
2010
This video demonstrates a novel capsulorhexis technique in modern cataract surgery. Capsulorhexis is the most difficult and important part of phacoemulsification surgery.
02:12
The Wave Nature of Light
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2020
The nature of light has been a subject of inquiry since antiquity. In the seventeenth century, Isaac Newton performed experiments with lenses and prisms and was able to demonstrate that white light consists of the individual colors of the rainbow combined together. Newton explained his optics findings in terms of a "corpuscular" view of light, in which light was composed of streams of extremely tiny particles traveling at high speeds according to Newton's laws of motion. Others in the...
09:20
The Assembly and Application of 'Shear Rings': A Novel Endothelial Model for Orbital, Unidirectional and Periodic Fluid Flow and Shear Stress
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Cited by 10 •
2016
Different levels and patterns of fluid shear are known to modulate endothelial gene expression, phenotype and susceptibility to disease. We discuss the assembly and use of 'shear rings': a model that produces unidirectional, periodic shear stress patterns. Shear rings are simple to assemble, economical and can produce high cell yields.
FAQs
The key quantitative step is converting measured shear-wave speed into an estimate of elastic properties, including shear modulus. Faster or slower propagation therefore becomes a measurable indicator of mechanical behavior rather than only a motion signal. In bioengineering studies, this conversion allows researchers to compare the stiffness of cells, hydrogels, engineered tissues, or native organs using a common mechanical readout.
Focused acoustic radiation force and ultrafast ultrasound serve complementary roles. The acoustic push creates a controlled displacement and launches the transverse wave, while ultrafast imaging follows the resulting motion over time. Separating wave generation from motion tracking is important because the final stiffness estimate depends on both producing a measurable disturbance and recording how that disturbance travels through the sample.
Because measurements are obtained without extensive sampling or destructive testing, shear wave imaging can assess mechanical properties while preserving the specimen for continued study. This is especially useful for bioengineered constructs whose properties may change during maturation. Repeated characterization can support evaluation of tissue development or biomaterial performance without relying solely on endpoint measurements.
A typical workflow begins by applying focused acoustic radiation force to the tissue or material. The induced displacement generates shear waves, and ultrafast ultrasound tracks their motion. The recorded propagation behavior is then converted into elastic-property estimates. This sequence links an applied mechanical stimulus, measured wave motion, and quantitative stiffness characterization in a single noninvasive assessment.
In bioengineering, the method can characterize cells, hydrogels, engineered tissues, and native organs. These targets span biological components, biomaterial matrices, constructed tissue models, and organ systems, allowing mechanical measurements across different stages of development and translation. Its value lies in providing quantitative information that helps relate material or tissue state to stiffness-related changes.
Researchers can use the resulting measurements to evaluate disease-related mechanical changes, monitor tissue maturation, and optimize biomaterials or regenerative constructs. Each application uses stiffness information differently: disease studies examine altered mechanics, maturation studies follow developmental change, and design studies use measurements to refine construct or material choices. These uses connect imaging data with research and clinical-translation goals.