Tunable Acoustic Gradient Lens

Tunable Acoustic Gradient Lens is an acoustic device that shapes and redirects sound by creating a controllable spatial gradient in acoustic properties, enabling dynamic control of wavefronts and focus. It works because sound travels at different speeds through regions with differing acoustic impedance or sound velocity; changing the gradient alters refraction, focal position, and beam direction without requiring mechanical movement. In bioengineering, this capability supports adaptable ultrasound imaging, localized acoustic stimulation, and manipulation of cells or particles. By providing reconfigurable, contact-free control of acoustic energy, the lens can improve precision and flexibility in systems for diagnostics, research, and emerging therapeutic technologies.

Tunable Acoustic Gradient Lens - Related Videos

Research

JoVE Journal - Bioengineering

Switchable Acoustic and Optical Resolution Photoacoustic Microscopy for In Vivo Small-animal Blood Vasculature Imaging

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Cited by 8 •

2017

Here a switchable acoustic resolution (AR) and optical resolution (OR) photoacoustic microscopy (AR-OR-PAM) system capable of both high resolution imaging at shallow depth and low resolution deep tissue imaging on the same sample in vivo is demonstrated.

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

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Cited by 4 •

2013

In this video we first describe fabrication and operation procedures of a surface acoustic wave (SAW) acoustic counterflow device. We then demonstrate an experimental setup that allows for both qualitative flow visualization and quantitative analysis of complex flows within the SAW pumping device.

Eye Lens Dissection: A Technique to Observe Zebrafish Lens Morphology

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2023

This video describes the protocol which is developed to dissect adult and larval zebrafish lenses to analyze cortical lens morphology and structural integrity of the lens sutures.

Research

JoVE Journal - Neuroscience
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Stereotaxic Viral Injection and Gradient-Index Lens Implantation for Deep Brain In Vivo Calcium Imaging

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Cited by 5 •

2021

Miniscope in vivo calcium imaging is a powerful technique to study neuronal dynamics and microcircuits in freely behaving mice. This protocol describes performing brain surgeries to achieve good in vivo calcium imaging using a miniscope.

Education

JoVE Science Education - Chemistry

Density Gradient Ultracentrifugation

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2023

Density gradient ultracentrifugation is a common technique used to isolate and purify biomolecules and cell structures. This technique exploits the fact that, in suspension, particles that are more dense than the solvent will sediment, while those that are less dense will float. A high-speed ultracentrifuge is used to accelerate this process in order to separate biomolecules within a density gradient, which can be established by layering liquids of decreasing density in a centrifuge tube. The...

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