Cartilage Tissue

Cartilage tissue is a specialized connective tissue that provides flexible support, smooth movement, and resistance to compression in structures such as joints, the respiratory tract, and the external ear. Its chondrocytes produce and maintain an abundant extracellular matrix rich in collagen and proteoglycans, while the tissue’s limited blood supply slows nutrient delivery and repair. Biology studies distinguish hyaline, elastic, and fibrocartilage based on matrix composition and mechanical properties. Understanding these differences supports research on skeletal development, joint function, osteoarthritis, tissue engineering, and strategies to improve cartilage regeneration after injury.

Cartilage Tissue - Related Videos

Research

JoVE Journal - Bioengineering

Human Cartilage Tissue Fabrication Using Three-dimensional Inkjet Printing Technology

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Cited by 85 •

2014

The methods described in this paper show how to convert a commercial inkjet printer into a bioprinter with simultaneous UV polymerization. The printer is capable of constructing 3D tissue structure with cells and biomaterials. The study demonstrated here constructed a 3D neocartilage.

Education

JoVE Core - Cell Biology

Growth of Cartilage and Bone Tissue

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2023

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...

Harvesting Articular Cartilage From Joints of an Equine Donor: A Surgical Procedure to Isolate Vascular Connective Tissue From Cadaveric Joints of an Equine Donor

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2025

In this video, we demonstrate the extraction of articular cartilage from an equine cadaveric joint. The isolated articular cartilage can be used for further downstream analysis.

Cresyl Violet Staining of Tissue Sections: A Staining Procedure to Visualize Cartilage and Bones in Frozen Mouse Embryo Sections

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2025

This video describes cresyl violet staining procedure to visualize bones and cartilage in coronal sections of frozen mouse embryos. This staining technique helps to differentiate bones and cartilage with distinct colors from the surrounding tissues.

Safranin-O Staining: A Method to Visualize the Structural Integrity and Cellularity of Cartilage

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2025

In this video, we demonstrate a staining procedure for cartilage using safranin-orange. This method helps visualize the cartilage and detect any damage.

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