Catabolism Anabolism

Catabolism and anabolism are the two complementary divisions of metabolism, the network of chemical reactions that sustains cellular life. Catabolic pathways break down complex molecules such as carbohydrates, lipids, and proteins into smaller products, capturing released energy in ATP and reduced electron carriers, whereas anabolic pathways use energy and molecular building blocks to assemble cellular components. Enzymes regulate these pathways through stepwise reactions, and cells couple energy-releasing catabolism to energy-requiring anabolism to support growth, repair, storage, and reproduction. In biology, understanding this balance helps explain nutrient use, cellular energy flow, metabolic adaptation, and disorders that arise when metabolism is disrupted.

Catabolism Anabolism - Related Videos

Education

JoVE Core - Anatomy and Physiology

Types of Chemical Reactions: Anabolic and Catabolic

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2023

The first law of thermodynamics holds that energy can neither be created nor destroyed—it can only change form. An organism's essential function is to consume (ingest) energy and molecules in the foods we eat, convert some of it into fuel for movement, sustain our body functions, and build and maintain our body structures. There are two types of reactions that accomplish this: anabolism and catabolism. Anabolism is the process of combining smaller, simpler molecules into larger, more complex...

Carbohydrate Catabolism

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2025

Carbohydrate catabolism is a fundamental process in cellular metabolism that enables energy extraction from glucose through two primary pathways: cellular respiration and fermentation. Both pathways begin with glycolysis, which operates independently of oxygen availability.Glycolysis: A Shared Starting PointGlycolysis is an oxygen-independent process that breaks down glucose into two molecules of pyruvic acid. During this process, a net gain of two ATP molecules and two NADH molecules is...

Lipid Catabolism

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2025

Triglycerides serve as crucial long-term energy storage molecules in microorganisms, providing a dense source of metabolic energy. Their breakdown is mediated by lipases, which hydrolyze triglycerides into glycerol and free fatty acids. Each of these components follows distinct metabolic pathways, ultimately contributing to ATP synthesis and cellular energy homeostasis.Glycerol MetabolismGlycerol, released from triglyceride hydrolysis, is phosphorylated by glycerol kinase to form...

Amino Acid Catabolism

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2025

Microorganisms rely on proteins as an essential carbon and energy source, particularly in environments with limited polysaccharides or lipids. However, proteins are too large to cross the plasma membrane unaided, necessitating enzymatic degradation. Microbes secrete extracellular proteases and peptidases that hydrolyze proteins into peptides, which can then be transported across the membrane. Once inside the cell, intracellular proteases degrade these peptides into free amino acids, which...

Research

JoVE Journal - Cancer Research

Exploring the Regulation of Lipid Droplet Catabolism through Lipophagy

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2025

Lipophagy is a selective form of autophagy that involves the degradation of lipid droplets. Dysfunctions in this process are associated with cancer development. However, the precise mechanisms are not yet fully understood. This protocol describes quantitative imaging approaches to better understand the interplay between autophagy, lipid metabolism, and cancer progression.

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