Cremaster Muscle

Cremaster muscle is a thin layer of skeletal muscle that surrounds the spermatic cord and testes, helping regulate testicular position and temperature in male reproductive biology. It contracts to elevate the testes toward the inguinal canal when exposed to cold or activated by touch, and relaxes to lower them. This response forms the cremasteric reflex, involving sensory input from the ilioinguinal nerve and motor output through the genital branch of the genitofemoral nerve. Studying this muscle connects anatomy, neurophysiology, and reproductive function, while evaluating the reflex can help assess nerve pathways and identify abnormalities such as testicular torsion.

Cremaster Muscle - Related Videos

Research

JoVE Journal - Biology
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The Mouse Cremaster Muscle Preparation for Intravital Imaging of the Microcirculation

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Cited by 46 •

2011

A tissue preparation is described for visualization and experimental manipulation of the living microcirculation. In anesthetized male mice, the thin, highly vascularized cremaster muscle is prepared for intravital microscopy to study microvascular networks including arterioles, capillaries and venules. This preparation is readily adapted for rats and hamsters.

Research

JoVE Journal - Biology

Intravital Microscopy of the Microcirculation in the Mouse Cremaster Muscle for the Analysis of Peripheral Stem Cell Migration

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Cited by 4 •

2013

Intravital microscopy of the mouse M. cremaster microcirculation offers a unique and well-standardized in vivo model for the analysis of peripheral bone marrow stem cell migration.

Visualization and Quantification of the Cell-free Layer in Arterioles of the Rat Cremaster Muscle

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Cited by 1 •

2016

This study demonstrates the surgical preparation of the rat cremaster muscle for the visualization of the in vivo cell-free layer. Considerable factors affecting the accuracy of the cell-free layer width measurement are discussed in this study.

Real-time Digital Imaging of Leukocyte-endothelial Interaction in Ischemia-reperfusion Injury (IRI) of the Rat Cremaster Muscle

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Cited by 10 •

2012

Digital intravital epifluorescence microscopy of postcapillary venules in the cremasteric microcirculation is a convenient method to gain insights into leukocyte-endothelial interaction in vivo in ischemia-reperfusion injury (IRI) of striated muscle tissue. We here provide a detailed protocol to safely perform the technique and discuss its applications and limitations.

Leukocyte Infiltration of Cremaster Muscle in Mice Assessed by Intravital Microscopy

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Cited by 7 •

2020

Here, we show how to perform intravital microscopy on post-capillary venules of the mouse cremaster muscle. Commonly applied to different models of inflammation and sepsis, particularly those induced by chemokines and cytokines, we highlight its relevance in the study of muscolopathies involving exaggerated muscular leukocyte infiltration.

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